SLIC: a new rapid diagnostic test for urinary infections
Research type
Research Study
Full title
SLIC: a feasibility study of a novel rapid diagnostic test for uncomplicated urinary tract infections in primary care.
IRAS ID
244611
Contact name
Stephen H Gillespie
Contact email
Sponsor organisation
University of Saint Andrews
Clinicaltrials.gov Identifier
Application Number 2018072301164199, MHRA Registration
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Resistance to antibiotics is an increasing public health concern world-wide, and a threat to patient safety. Infections that were easily treatable in the past, can no longer be cured if bacteria develop resistance. Rapid diagnostics provide the ability of detecting infection in a symptomatic patient in a more precise, and timely manner. SLIC is a novel tool based on laser technology, able to detect bacterial presence in urine in less than 10 minutes (standard NHS GP consultation time), with extra ability to test bacterial resistance to commonly used antibiotics, with all this process taking less than 30 minutes. The main aim of the present study is to assess the sensitivity and specificity of the test, comparing SLIC results with standard laboratory culture. If SLIC is shown to be effective, it proving to be a potential outstanding resource for improving the management of patients with suspected urinary infection presenting to primary care, and reducing inappropriate antibiotic use, which is the main factor driving resistance.
REC name
South East Scotland REC 01
REC reference
18/SS/0110
Date of REC Opinion
10 Sep 2018
REC opinion
Favourable Opinion