Single Use NPWT Pre-Registration Study

  • Research type

    Research Study

  • Full title

    NPWT Pre-Registration Study: A Prospective, Multicentre Trial to assess performance, and safety of a single-use negative pressure system.

  • IRAS ID

    236897

  • Contact name

    Steven Jeffery

  • Contact email

    sjeffery@nhs.net

  • Sponsor organisation

    Smith & Nephew

  • Clinicaltrials.gov Identifier

    SURG 37295, NIHR CRN; Application being processed, Clintrials.gov

  • Duration of Study in the UK

    0 years, 5 months, 1 days

  • Research summary

    Smith & Nephew are assessing a new single use NPWT system.
    There is a significant amount of clinical evidence to show that NPWT may reduce oedema, increase healing and reduce chance of infection, through maintenance of pressure therapy, in closed incisions, and some limited clinical evidence on skin grafts. The proposed clinical strategy is to conduct a study assessing performance, and safety of the new single use NPWT system in order to assess whether the same benefits of other NPWT systems on the market can be applied to therapy provided with the new system. Subjects with abdominal incisions, skin grafts and knee incisions following knee surgery will be recruited to the study and receive NPWT for 7 days. The performance of the system will be logged by the device and acceptability of the device will be assessed by patient and clinician. Safety will be assessed with a 30 day follow up to assess complications and device related events.

  • REC name

    North West - Greater Manchester East Research Ethics Committee

  • REC reference

    18/NW/0359

  • Date of REC Opinion

    20 Nov 2018

  • REC opinion

    Further Information Favourable Opinion