Single-cell characterization of human skin
Research type
Research Study
Full title
Single-cell characterization of human skin
IRAS ID
237007
Contact name
Fiona Watt
Contact email
Sponsor organisation
King’s College London
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 6 months, 1 days
Research summary
Human tissues are composed of an array of diverse cell types and structural elements. Normal tissue function in health and disease is dependent upon a complex interplay between these different components. To date it has been challenging to dissect these relationships at a single cell level in human tissues. We are using the human skin and a model system to dissect the complex cellular relationships that govern normal tissue function in health and disease. In order to accomplish this we are employing novel techniques, including single-cell RNA sequencing, which permit the analysis of cell function at an unprecedented level of detail at the single-cell level. Data from this research will contribute to the human cell atlas project, an international collaborative project to establish gene expression maps for each cell type in the human body.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
19/NE/0063
Date of REC Opinion
30 Apr 2019
REC opinion
Further Information Favourable Opinion