SIFTI-2

• Research type

  Research Study

• Full title

  A Multi-centre, Prospective Study to Examine the Relationship between Neutrophil Function and Sepsis in Adults and Children with Severe Thermal Injuries

• IRAS ID

  200366

• Contact name

  Naiem Moiemen

• Contact email

  Naiem.Moiemen@uhb.nhs.uk

• Sponsor organisation

  UHBFT

• Duration of Study in the UK

  2 years, 0 months, 1 days

• Research summary

  The study aims to validate neutrophil function, immature granulocyte and plasma free DNA levels as predictive diagnostic biomarkers of sepsis in burn patients. Inclusion criteria includes healthy volunteers, patients aged 5-15 years old with burns affecting 10% or less TBSA and patients aged 16 or above with burns affecting >15% TBSA. The study involves taking blood, tissue and urine samples. It will be primarily based in University Hospitals Birmingham and Birmingham Children's hospital and should last for 2 years

• REC name

  West Midlands - Coventry & Warwickshire Research Ethics Committee

• REC reference

  16/WM/0217

• Date of REC Opinion

  7 Jun 2016

• REC opinion

  Favourable Opinion