SHUNT study
Research type
Research Study
Full title
On line Surveillance of established haemodialysis arteriovenous fistula utilising Fresenius Therapy Monitoring System and European Clinical Data System (Euclid)
IRAS ID
254813
Contact name
Sunil Bhandari
Contact email
Sponsor organisation
Hull and East Yorkshire Hospitals NHS Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Patients on haemodialysis require some form of an access to their blood circulation system so that their blood flows easily through the dialysis circuit and is cleaned efficiently. The best way to gain such access is to surgically make a join between an artery and vein in one arm. This is called an arteio-venous fistula (AVF). An AVF is a "life line" for dialysis patients; if it stopped working (i.e. failed), patients can no longer dialyse. This results in the need for temporary insertion of a line into the neck which is not ideal. If one was able to monitor these AVFs closely using a reliable technique then it might be possible to intervene to correct an impending problem before the AVF fails.
There have been several methods proposed to monitor AVFs; but we propose that using the Fresenius Therapy Monitoring System (F-TDMS) and European Clinical Data system (EuCliD) may be useful in preserving an AVF or indicating when prompt intervention is needed. To date, the research on this is limited. In the SHUNT study, we examine if this simple and easily accessible method of surveillance of the AVF during dialysis is beneficial. We will monitor 100 suitable participants and follow-up these participants for 1 year with regular monitoring. This study is needed before this method of monitoring can be put into routine clinical practice. In addition we will look at other effects the use of this surveillance system has on the fistula and participant.REC name
London - Chelsea Research Ethics Committee
REC reference
19/LO/0394
Date of REC Opinion
26 Feb 2019
REC opinion
Favourable Opinion