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Sheffield MND Care and Research Centre Database

  • Research type

    Research Database

  • IRAS ID

    293450

  • Contact name

    Pamela Shaw

  • Contact email

    pamela.shaw@sheffield.ac.uk

  • Research summary

    Sheffield MND Care and Research Centre Database

  • REC name

    Yorkshire & The Humber - Sheffield Research Ethics Committee

  • REC reference

    21/YH/0093

  • Date of REC Opinion

    14 May 2021

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    The database contains information from clinical records and outpatient clinic visits of Motor Neurone Disease (MND) patients. All patients who attend the Royal Hallamshire Hospital will be included on the database. Details of patient disease progression and clinical care is documented on the database.

  • Research programme

    The database will support the MND research community in Sheffield and their collaborators. Any outcomes of the research will provide information to improve the care and treatment of MND patients. Specifically, the areas of research that are covered under this protocol and ethical approval are: - MND-related studies investigating the genetic causes and potential environmental predispositions of the disease. - MND-related studies that will facilitate and support the improvements in clinical care and advance the knowledge of clinicians and researchers in attempting to find new treatments and methods of improving quality of life for MND patients. - Studies looking for specific trends or correlations in the data, aiding in understanding of the disease progression and investigating potential therapeutic benefits or targets for future therapies. - Studies to enable biomathematicians to build probabilistic models that can link clinical data to environmental risk factors and genetic risk factors.

  • Research database title

    Sheffield MND Care and Research Centre Database

  • Establishment organisation

    Sheffield Teaching Hospitals NHS Foundation Trust

  • Establishment organisation address

    Clinical Research & Innovation Office Sheffield, D Floor, Royal Hallamshire Hospital

    Sheffield Teaching Hospitals NHS Foundation Trust

    Glossop Road, Sheffield

    S10 2JF