Severe Paediatric Asthma Collaborative in Europe (SPACE)

• Research type

  Research Database

• IRAS ID

  358189

• Contact name

  Norrice Liu

• Contact email

  n.liu@qmul.ac.uk

• Research summary

  Severe Paediatric Asthma Collaborative in Europe (SPACE)

• REC name

  London - Bloomsbury Research Ethics Committee

• REC reference

  26/LO/0307

• Date of REC Opinion

  15 May 2026

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Data will be collected in 2 distinct fields: baseline study entry and follow-up form.

  List of variables:
  • Basic case information including age, gender, ethnicity
  • Screening details: confirmation of asthma (symptoms, spirometry,
  treatments)
  • Criteria for exclusion (list of conditions that might mimic asthma)
  • Other comorbidities (chronic diseases) and risk factors
  • Smoking history
  • Lung function
  • Investigations results such as FeNO, sputum and blood eosinophil counts; Total IgE; Specific IgE; Skin prick test
  • Lung imaging; Bronchoscopy
  • Asthma Control questionnaires scores
  • Treatment adherence questionnaire scores
  • Quality of life questionnaire scores
  • Treatments and side effects

• Research programme

  N/A

• Research database title

  Severe Paediatric Asthma Collaborative in Europe (SPACE)

• Establishment organisation

  University of Dundee

• Establishment organisation address

  Tayside Medical Sciences Centre

  Research & Development Office

  George Pirie Way, Dundee

  DD1 9SY