Secondary analysis of COBRA Snaith Hamilton Pleasure Scale Data
Research type
Research Study
Full title
Secondary analysis of COBRA Snaith Hamilton Pleasure Scale Data
IRAS ID
253440
Contact name
Barnaby Dunn
Contact email
Sponsor organisation
University of Exeter
Duration of Study in the UK
2 years, 3 months, 1 days
Research summary
Depression is a major public health problem and better talking therapies are needed. It has been proposed that current depression talking therapies are effective at reducing negativity (thinking/feeling sad) but fail to repair positivity (thinking/feeling happy). To test this claim, we wish to run secondary analyses of the COBRA trial comparing two of the current gold standard therapies for depression – behavioural activation (BA) and cognitive behavioural therapy (CBT) – in terms of how well they repair positivity. We will look at how many people show a meaningful amount of improvement in positivity and also estimate the average amount of improvement in positivity 6m, 12m and 18m after treatment. If these existing treatments do fail to repair positivity, this is will be clinically important as we now know that those who struggle to experience positivity are more likely to stay depressed for longer, to not get better during treatment, and to become depressed again in the future.
REC name
West of Scotland REC 5
REC reference
18/WS/0188
Date of REC Opinion
10 Oct 2018
REC opinion
Favourable Opinion