SEARCH-ED

  • Research type

    Research Study

  • Full title

    Strategy for EArly Recognition of Cancer, COPD & Heart failure in the Emergency Department

  • IRAS ID

    360783

  • Contact name

    David Lowe

  • Contact email

    david.lowe@glasgow.ac.uk

  • Sponsor organisation

    West of Scotland Innovation Hub

  • Duration of Study in the UK

    1 years, 3 months, 0 days

  • Research summary

    SEARCH-ED is a research study which is running in Emergency Department (ED) of the Queen Elizabeth University Hospital. The aim of the study is to find out if using an artificial intelligence (AI) computer programme can help doctors diagnose heart and lung problems from chest x-rays. The computer programme is made by Annalise Enterprise. It is approved for use in the UK, US and EU. Studies have been carried out previously to make sure it is safe to use and that it can detect signs of heart and lung problems.

    Many people who come to ED have a chest x-ray. Chest x-rays can show signs of heart or lung problems, which might be causing a patient’s symptoms. All doctors can interpret chest x-rays. However, doctors who specialise in interpreting scans (radiologists) also provide an expert report for chest x-rays, describing what they have found. It can take a long time for chest x-ray reports to come back. Sometimes, doctors might miss signs of heart or lung problems.

    We want to see if using a computer programme to help doctors interpret chest x-rays could lead to more patients getting an accurate diagnosis. We want to compare how many people are diagnosed with heart or lung problems (COPD, heart failure or lung cancer) for the first time when doctors have access to the computer programme results, in comparison to when they don’t. Patients older than 18 who have a chest x-ray in ED will be included.

    Patients with chest x-rays flagged by the computer programme for heart failure or COPD will be invited to an outpatient clinic for further assessment post-discharge, providing they have not been referred for testing or had testing previously.
    All patients with chest x-rays flagged for lung cancer will be reviewed and acted on by the study radiologist.

  • REC name

    South West - Cornwall & Plymouth Research Ethics Committee

  • REC reference

    25/SW/0124

  • Date of REC Opinion

    29 Oct 2025

  • REC opinion

    Favourable Opinion