Scores on the Door: What people most want from antiretroviral therapy
Research type
Research Study
Full title
Scores on the Door – What people most want from Antiretroviral Therapy
IRAS ID
281188
Contact name
Derek Macallan
Contact email
Sponsor organisation
St George's, University of London
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Antiretroviral therapy has revolutionised the outlook for people living with HIV (PLWH) and treatment is now recommended for all infected people at any stage of their disease. There are now many options for treatment but few are without some drawback. For some, this is a current issue such as a side-effect, for some a future issue, such as bone health, and for others it is more about convenience. How these different aspects are weighed up by patients has been explored to some degree in the past but we wish to apply a novel tool, the desirability of outcome ranking (DOOR) approach to explore which factors count more in patients’ own minds. We will do this by asking PLWHA on treatment to rank storyboards of an imaginary patient’s experience. Participants will be given five storyboards to rank in order of “best outcome” to “worst outcome”. Each storyboard will be assembled by combining brief narratives in five domains: Treatment difficulty, Treatment failure, Long-term complication, Side-effect, and Life event. Rankings will be collated to determine the relative weighting given by patients to each domain. These weightings will be related to basic demographic data. The results of this study will be used to inform healthcare practitioners of the relative values their patients are likely to attribute to different treatment attributes and hence shape treatment decisions in a more patient-centred fashion.
REC name
London - Brent Research Ethics Committee
REC reference
20/PR/0249
Date of REC Opinion
29 Oct 2020
REC opinion
Further Information Favourable Opinion