Scleroderma and Raynaud's Research Bank (Renewal 2019)

• Research type

  Research Tissue Bank

• IRAS ID

  258685

• Research summary

  Scleroderma and Raynaud's Research Bank (SRRB)

• REC name

  North West - Haydock Research Ethics Committee

• REC reference

  19/NW/0163

• Date of REC Opinion

  4 Jun 2019

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Blood samples and extracted DNA samples are stored at the Arthritis Research UK Epidemiology Unit located within the Stopford Building, University of Manchester. These are collected from patients at Salford Royal NHS Foundation Trust.

  Skin Biopsies are stored at the Stopford Building, University of Manchester. These are collected from patients at Salford Royal NHS Foundation Trust.

  Calcinosis samples are stored at the University of Manchester. They are collected from patients at Salford Royal NHS Foundation Trust or by the patients themselves if they naturally extrude through the skin. Calcinosis samples from patients with calcific tendinitis of the shoulder are collected during surgery by the orthopaedic teams at Salford Royal NHS Foundation Trust and Trafford Hospital, Central Manchester Foundation Trust.

  Serum Samples are stored in the Clinical Science Building, Salford Royal NHS Foundation Trust. Samples are collected from patients at Salford Royal NHS Foundation Trust.

  Capillaroscopy and Thermography images are stored on secure servers maintained by Salford Royal NHS Foundation Trust. Samples are collected from patients at Salford Royal NHS Foundation Trust.

  Clinical and demographic data are held on secure servers maintained by the University of Manchester.

  Custodianship of the Bank as a whole is held by the University of Manchester and samples are held under the University's Human Tissue Authority Licence.

• Research programme

  The Bank will be used for research into scleroderma (both systemic sclerosis and localised scleroderma also termed morphoea), Raynaud's phenomenon and related disorders. Scleroderma and related disorders are rare and there is a genuine need for collaborative and multi-centre research to generate sufficient sample sizes for research into the pathogenesis and underlying disease process of scleroderma and primary Raynaud's phenomenon.

• Storage license

  12172

• RTBTitle

  Scleroderma and Raynaud's Research Bank (SRRB)

• Establishment organisation

  University of Manchester

• Establishment organisation address

  Oxford Road

  Manchester

  M13 9PL