SARCOFALLS study v 1.0

  • Research type

    Research Study

  • Full title

    Sarcopenia in an older population at high risk of falls

  • IRAS ID

    173054

  • Contact name

    Tahir Masud

  • Contact email

    tahir.masud@nuh.nhs.uk

  • Sponsor organisation

    NUH NHS Trust

  • Duration of Study in the UK

    1 years, 1 months, 1 days

  • Research summary

    This is primarily a study into the prevalence of Sarcopenia in a fallers population referred to secondary care falls services to inform future research on this condition.

    Criteria for identifying Sarcopenia are low muscle mass and function (Cruz-Jentoft et al., 2010). Sarcopenia has been linked to reduced physical ability, quality of life and increased mortality (Cruz-Jentoft et al., 2010). A systematic review into the prevalence of and interventions for Sarcopenia (Crutz-Jentoft et al., 2014) stated that more well designed studies with a large enough sample size to identify prevalence and risk factors for Sarcopenia in well-defined populations are needed.

    Low muscle power is a risk factor for falls and has been shown to increase the risk of falls by more than four times (Rubenstein and Josephson 2006). However the prevalence of Sarcopenia in a falls population is not known. As treatments for Sarcopenia are being developed such as exercise, essential amino acids and protein supplements it is important to know the prevalence of Sarcopenia in this population.

    The results of this study will be used to inform the design of a future feasibility study and grant application which will investigate the use of Leucine plus an exercise programme versus the exercise programme alone in a population at high risk of falls.

  • REC name

    East Midlands - Nottingham 2 Research Ethics Committee

  • REC reference

    15/EM/0175

  • Date of REC Opinion

    18 Jun 2015

  • REC opinion

    Further Information Favourable Opinion