(Salford sub-study) AKI and Readmissions Study v1.0
Research type
Research Study
Full title
The Role of Kidney Diseases in Readmissions and Kidney Outcomes among People Discharged after a Hospital Admission - External validation in Salford
IRAS ID
278612
Contact name
Simon Sawhney
Contact email
Sponsor organisation
University of Aberdeen
Duration of Study in the UK
3 years, 0 months, 5 days
Research summary
Acute kidney injury (AKI) is common (1 in 7 admissions) and serious (fourfold increased mortality). Up to 1 in 3 people with AKI return to hospital as an emergency within 90 days. International guidelines and kidney patient groups call for improvements in how we identify and care for people leaving hospital who will fare less well.
This study aims to identify and improve the care of high risk people leaving hospital. To achieve this, we will first develop clinical risk tools to test across the UK regions and in different time periods (starting with Grampian and then testing in Salford data).
These tools will combine information available in electronic health records to identify people who have a high risk of an emergency readmission to hospital.
We will then study people admitted to hospitals in Grampian and Salford in greater detail to understand why some people do less well. We will study whether people with kidney diseases such as AKI are more prone to readmissions and whether this is related to differences in health (current and previous health conditions and treatments) or the care they receive (the timing of clinical consultations and blood tests – outpatient, inpatient, A&E). This information will help us determine how we can best assess future risks when caring for people with kidney diseases. The study will also help us determine when and how could intervene at the right time to improve the care of high risk people.We already have permission to develop the tools in Grampian. In this project we request permission to validate these tools in a separate population (Salford) to assess whether clinical tools and findings are generalisable.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
20/EE/0081
Date of REC Opinion
10 Mar 2020
REC opinion
Favourable Opinion