Safety and Performance of IRIS V2 System

  • Research type

    Research Study

  • Full title

    Compensation for blindness with the Intelligent Retinal Implant System (IRIS V2) in patients with retinal dystrophy

  • IRAS ID

    198526

  • Contact name

    Karine Chevrie

  • Contact email

    kchevrie@pixium-vision.com

  • Sponsor organisation

    Pixium Vision

  • Clinicaltrials.gov Identifier

    NCT02670980

  • Duration of Study in the UK

    6 years, 0 months, 1 days

  • Research summary

    An open-label clinical trial to evaluate the safety and performance of a newly developed Intelligent Retinal Implant System (IRIS V2) in patients with retinal dystrophy. IRIS V2 is designed to restore some limited visual perception in persons who have lost their sight due to the degeneration of photoreceptor cells.

    The IRIS V2 consists of 3 main components

    1) A visual interface (a camera with data transmitters mounted on spectacles)
    2) A pocket processor (processes data to generate retinal stimulation commands)
    3) A retinal implant (receives commands from the visual interface to stimulate the retina)

    Up to 10 patients will be implanted. Depending on the number of screening failures, up to 20 patients will be enrolled across the EU with retinitis pigmentosa, cone rod dystrophy or choroideremia. Participants will be followed for up to 3 years post implant.

  • REC name

    London - Dulwich Research Ethics Committee

  • REC reference

    16/LO/0409

  • Date of REC Opinion

    11 Apr 2016

  • REC opinion

    Further Information Favourable Opinion