Safety and efficacy of a novel cartilage repair construct (CARE01)
Research type
Research Study
Full title
Safety and efficacy of a novel, cell-free cartilage repair construct (code: CARE01) in the treatment of focal chondral defects involving the femorotibial compartment and femoral trochlea of the knee joint.
IRAS ID
162399
Contact name
Sanjiv Jari
Contact email
Sponsor organisation
TRB Chemedica (UK) Ltd
Clinicaltrials.gov Identifier
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
The primary working hypothesis is that the CARE01 construct, made up of a collagen matrix containing HA, is safe and suitable as a cell-free matrix to support haemostasis, as a cover for the cartilage lesion and eventually to enhance cartilage regeneration in a one-step surgical procedure.
REC name
North West - Greater Manchester East Research Ethics Committee
REC reference
16/NW/0198
Date of REC Opinion
20 Apr 2016
REC opinion
Further Information Favourable Opinion