RPGR Validation of a Vision-Guided Mobility Assessment (VMA)

• Research type

  Research Study

• Full title

  A study in normally-sighted participants and in participants with RPGR associated X-linked Retinitis Pigmentosa (XLRP) to validate the Vision-Guided Mobility Assessment for use in natural history studies and therapeutic clinical trials of adult, adolescent and child patients with Inherited Retinal Diseases (IRDs).

• IRAS ID

  289223

• Contact name

  Michel Michaelides

• Contact email

  michel.michaelides@ucl.ac.uk

• Sponsor organisation

  MeiraGTx UK II ltd

• Duration of Study in the UK

  1 years, 1 months, 2 days

• Research summary

  This is a study in normally-sighted participants and in participants with X-linked Retinitis Pigmentosa (XLRP) associated with variants in the retinitis pigmentosa guanosine triphosphatase regulator (RPGR) gene (RPGR-XLRP) to validate the Vision-Guided Mobility Assessment commonly referred to as a maze. Validation of this assessment will allow for use in natural history studies and therapeutic clinical trials of adult, adolescent and child patients with Inherited Retinal Diseases (IRDs).

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  20/EM/0268

• Date of REC Opinion

  8 Dec 2020

• REC opinion

  Further Information Favourable Opinion