Root cause analysis of CVD prevention
Research type
Research Study
Full title
Root cause analysis of cardiovascular disease prevention and risk factor management failure
IRAS ID
141979
Contact name
Charlie Davie
Contact email
Sponsor organisation
North Central London Research Consortium (NoCLoR)
Research summary
Despite mortality from cardiovascular disease (CVD) falling, it remains the biggest cause of death in the UK. CVD is also the commonest cause of long term disability. Approximately 1.2 million people in the UK are living with the physical and psychological consequences of a stroke. A further 2.7 million will have suffered from coronary artery disease. CVD is estimated to cost the UK economy £30 billion a year.\n\nIn Camden, 247 people were admitted to hospital following a stroke in 2011/12 and 180 people with acute coronary syndromes (ACS) in 2011.\n\nThe causes of stroke and ACS are identifiable in over 90% of cases and many of these are treatable (e.g. anti-hypertension therapy, statins, antiplatelet therapies, thrombo-prophylaxis of AF, smoking cessation, diet and exercise).\n\nWe will identify all prospective patients with a diagnosis of acute stroke or ACS admitted from Camden to two acute sites across one year. \n\nA detailed database will be created. For each patient this will determine the type of stroke or ACS and identifiable risk factors together with a detailed analysis of health records. Every ACS and stroke incident within the population will be considered as if it were a serious incident, representing medical failure of CVD prevention. Root cause analysis methodology will be applied to investigate facts from case review and evidence collected from the experiences and insight of those involved in the patient’s care, experts in the clinical area, patients and their families and carers.\nWe will also interview patients to understand what factors influenced their previous adherence to or non-compliance to CVD risk management.\n\nThe objectives are to: \n• gain precise understanding of at risk populations\n• establish a basis for tailored interventions and pathways for primary and secondary prevention that address the specific population health needs and reduce the incidence of cardiovascular disease in Camden
REC name
East of England - Cambridgeshire and Hertfordshire Research Ethics Committee
REC reference
13/EE/0446
Date of REC Opinion
23 Dec 2013
REC opinion
Favourable Opinion