Role of urinary IFABP in diagnosis and predicting severity of NEC
Research type
Research Study
Full title
Predictive value of urinary intestinal fatty acid binding protein in preterm infants at risk of developing Necrotising Enterocolitis
IRAS ID
143216
Contact name
Ingo Jester
Contact email
Sponsor organisation
Birmingham Women's Hospital
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Necrotising enterocolitis (NEC) is a serious disease that affects the bowel of premature babies; a lot of babies die, many need emergency surgery and those who survive can have significant long term health problems. Identifying this disease earlier would allow more timely and effective treatment. We plan to measure a protein called intestinal fatty acid binding protein (IFABP), which is released from the bowel when it is damaged. This protein can be measured quite easily from a small sample of urine taken from a cotton wool ball in the nappy. The results of this study may allow earlier identification of NEC in the future leading to earlier treatment and fewer complications in babies who develop NEC.
REC name
North East - Newcastle & North Tyneside 1 Research Ethics Committee
REC reference
14/NE/1241
Date of REC Opinion
4 Feb 2015
REC opinion
Further Information Favourable Opinion