Role of ambulatory oxygen in improving the effectiveness of PR in COPD
Research type
Research Study
Full title
The role of ambulatory oxygen in improving the effectiveness of pulmonary rehabilitation for COPD patients
IRAS ID
188134
Contact name
Vijay Padmanaban
Contact email
Sponsor organisation
Imperial College London and Imperial College Healthcare NHS Trust
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Pulmonary rehabilitation (PR) is an exercise program tailored for patients with chronic lung disease that is a core part of the management of patients with Chronic Obstructive Pulmonary Disease (COPD). Many COPD patients develop low oxygen levels (desaturation) during exercise and this is often discovered when they are being evaluated for PR. Current practice is to administer oxygen to COPD patients with exercise-induced desaturation, but this is based on very limited evidence. This limited evidence relates to a short-term increase in exercise capacity and it is not known if this translates into longer term increases in activity or whether providing these patients with oxygen improves outcomes after PR.
In addition it is not known if patients given ambulatory oxygen continue to use it after completing PR. Evidence for a beneficial effect of oxygen would provide a more solid evidence base for its use. Conversely demonstration of no effect would allow reassessment of the use of oxygen and whether the costs are justified. Therefore the aims of this study are to assess the effects of oxygen on outcomes from PR and assess the usage of ambulatory oxygen following completion of PR.REC name
London - West London & GTAC Research Ethics Committee
REC reference
15/LO/2131
Date of REC Opinion
13 Jan 2016
REC opinion
Further Information Favourable Opinion