Role of adipose and skin derived cells and tissues in wound healing

  • Research type

    Research Study

  • Full title

    A laboratory study into the role of adipose tissue and cells in skin and other soft tissue wound healing, scar revision and tissue regeneration.

  • IRAS ID

    300558

  • Contact name

    Victoria Workman

  • Contact email

    v.workman@sheffield.ac.uk

  • Sponsor organisation

    University of Sheffield

  • Clinicaltrials.gov Identifier

    21879, Sheffield Teaching Hospitals project registration

  • Duration of Study in the UK

    4 years, 11 months, 31 days

  • Research summary

    This project will involve the collection of human skin, subcutaneous fat and lipoaspirate which would usually be discarded following routine procedures and will use these tissues for research. Our research project is interested in understanding the role of adipose tissue and skin tissue in tissue regeneration. We will use cells, tissues and factors generated from human skin and fat to perform lab based experiments looking at the role of these components on soft tissue wound healing, skin contraction and scarring and volume restoration.
    During the project we will also isolate cells, secreted factors and acellular tissues which will be used in future, as yet unknown research projects.
    It is anticipated that results from this study will guide future improvements in adipose therapies and skin regeneration.

  • REC name

    North East - Tyne & Wear South Research Ethics Committee

  • REC reference

    21/NE/0115

  • Date of REC Opinion

    22 Jun 2021

  • REC opinion

    Further Information Favourable Opinion