RobOLap-study
Research type
Research Study
Full title
A comparative study of post operative quality of life outcome after left sided colorectal cancer resection between Robotic-assisted, Open and Laparoscopic.
IRAS ID
278044
Contact name
Julie Dawson
Contact email
Sponsor organisation
Norfolk and Norwich University hospital
Duration of Study in the UK
1 years, 3 months, 0 days
Research summary
The current National bowel cancer data (NBOCAP data, 2019, https://www.nboca.org.uk/reports/short-report-2-2019/) shows that about 34% of the colorectal resections are performed by open (Laparotomy) approach. The uptake in minimal invasive rectal surgery is even lesser. This is primarily due to challenges posed by current minimally invasive surgery techniques. Two recent large randomized trials from America and Australasia have shown that laparoscopic surgery is inferior to open surgery in the treatment of rectal cancer with respect to oncological outcomes.
As a result, colorectal surgeons continue to perform open colorectal resections. However, there are evidence-based benefits of minimally invasive surgery, if performed safely underpinning the oncologic and surgical principles. These benefits include improvement in the quality of life of patients after surgery and enhanced recovery. This applies to benign pathology as well.
Quality of life questionnaires gives insight into the real physical, psychological and functional unmet needs of patients with cancer surgery. To our knowledge Postoperative quality of life have not been studied comparing open vs Laparoscopic vs Robotic left-sided colorectal resections.
Therefore, we propose a study comparing the postoperative quality of life after open vs laparoscopic vs robotic left-sided colorectal resections(cancer and benign). This study has two components. Interview of 8-9 patients in each arm of the study and the interview of the surgical team for a qualitative analysis of postoperative quality of life. The second component is Postal invitations will be sent to patients, with widely-used quality of life questionnaires: EORTC QLQ-C30/CR29, LARS score, EQ-5D-5L, OBAS pain score and PROMIS pain score.
This study will be expected to inform surgeons and patients to choose the appropriate approach for informed consenting. The post-operative patient-reported quality of life outcomes in the centre of discussion will help in not appropriate modality but also tailored surgery.
REC name
East of England - Cambridgeshire and Hertfordshire Research Ethics Committee
REC reference
20/EE/0060
Date of REC Opinion
14 Jun 2020
REC opinion
Further Information Favourable Opinion