Risk of endometrial and incidence of ovarian cancer after ablation
Research type
Research Study
Full title
The risk of endometrial cancer and incidence of ovarian cancer twenty-five years after endometrial resection or ablation in Northern Scotland. Does endometrial resection/ablation protect against endometrial carcinoma?
IRAS ID
215756
Contact name
Emmanouil Kalampokas
Contact email
Sponsor organisation
NHS Grampian
Duration of Study in the UK
0 years, 2 months, 1 days
Research summary
Endometrial resection or ablation (EA/R) is an alternative choice for hysterectomy for the treatment of heavy menstrual bleeding which was established slowly for a number of reasons. One of these was the view that women would not be protected from endometrial cancer and if they did get it would present late and be fatal.
Uterine endometrial cancer (EC) and ovarian cancer are the most common gynaecological malignancies.The true occurrence of EC and incidence of ovarian cancer after EA/R has not been established. The main aim of our study was to identify the risk of endometrial cancer and incidence of ovarian cancer after endometrial destruction.
To answer this we plan to do a retrospective cohort study in Aberdeen Royal Infirmary by using the anaesthetic books and pathology laboratory report database from February 1990 and December 1997.
These women will be followed up until 2015 and each woman will be matched by age to the annual observed incidence of endometrial cancer in the North of Scotland for each year from the date of EA/R until the end of 2014.
REC name
West of Scotland REC 3
REC reference
16/WS/0238
Date of REC Opinion
28 Feb 2017
REC opinion
Further Information Favourable Opinion