Rhinovirus Challenge in mild-moderate COPD Patients

• Research type

  Research Study

• Full title

  An exploratory study to establish a rhinovirus challenge model in patients with mild-moderate chronic obstructive pulmonary disease

• IRAS ID

  252772

• Contact name

  S Dave Singh

• Contact email

  dsingh@meu.org.uk

• Sponsor organisation

  Medicines Evaluation Unit (MEU) Ltd. (Investigator led study)

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  This is an exploratory study to assess the effect of RV challenge in patients with mild to moderate COPD. The proposed study will investigate the safety of RV challenge in COPD and its effect on symptoms, lung function and biological changes in the blood and the airways. This study is being carried out to see if Rhinovirus can be used to model exacerbations in COPD patients. It is hope this will enable new COPD drugs that target the airway inflammation exacerbated by the Rhinovirus to be assessed. The outcome from this study may help determine the use of this test in
  future research studies.

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  18/NW/0662

• Date of REC Opinion

  20 Nov 2018

• REC opinion

  Further Information Favourable Opinion