RH in hEDS/HSD
Research type
Research Study
Full title
Rectal hyposensitivity: A common pathophysiological mechanism in hypermobile Ehlers-Danlos syndrome patients with functional constipation
IRAS ID
297669
Contact name
Qasim Aziz
Contact email
Sponsor organisation
JRMO
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 2 months, 1 days
Research summary
Hypermobile Ehlers-Danlos (hEDS) syndrome is associated with many bodily systems, and patients with hEDS often have many medical conditions, including those related to the gastrointestinal system. Several studies have demonstrated that patients with hEDS have a high number of gastrointestinal symptoms, particularly constipation. Studies have looked to see what may cause these symptoms in patients with hEDS, however these studies are limited by small sample sizes and the absence of control groups. Consequently it is unclear what processes may be leading to symptoms such as constipation in these patients.
REC name
London - Bromley Research Ethics Committee
REC reference
21/PR/0628
Date of REC Opinion
26 May 2021
REC opinion
Further Information Favourable Opinion