REVRAMP
Research type
Research Study
Full title
Reverse RAMP pacing to terminate ventricular tachycardia ( REV-RAMP)
IRAS ID
224714
Contact name
Muzahir Tayebjee
Contact email
Sponsor organisation
LTHT
Duration of Study in the UK
2 years, 1 months, 31 days
Research summary
Cardiac pacing which involved stimulating the heart electrically with electrical wires that go into the heart is routine practice in the diagnosis and treatment of heart rhythm problems. Clinically this involved the fields of cardiac pacing and electrophysiology.
Patients who are at risk of sudden death because of serious heart rhythms that are a result of malfunction of the electrical system of the pumping chambers of the heart (ventricles) are generally implanted with specialised pacemakers that can defibrillate (shock) the heart if a nasty life threatening rhythm should result. Shocks are painful and in order to try and treat these rhythms without shocks, anti tachycardia pacing is performed (this is routine part of the device), which aims to interrupt the rhythm by stimulating the heart electrically. This does not always work and can destabilise the rhythm leading to a shock. REVRAMP is a novel modification of anti tachycardia pacing which involved stimulating the heart through the defibrillator wires in a different way. We want to determine whether this novel protocol works better than current
methods of antitachycardia pacing and is less likely to cause unstable rhythms.REC name
East Midlands - Derby Research Ethics Committee
REC reference
17/EM/0206
Date of REC Opinion
1 Aug 2017
REC opinion
Further Information Favourable Opinion