REVOLUTION
Research type
Research Study
Full title
Routine Evaluation of People Living with Cancer- Body Composition, Physical Function, Systemic Inflammatory Response, Quality of Life and Symptoms
IRAS ID
272861
Contact name
Richard Skipworth
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
9 years, 5 months, 7 days
Research summary
People with incurable cancer often have complex individual needs, however there are several common themes encountered when considering this group.
As cancer progresses there are series of interactions between the tumour and the patient, producing both local and systemic effects. This altered state of illness can have multiple ill effects including weight loss, fatigue, increased symptom burden and reduction in physical function which all contribute to a reduced quality of life.
These areas are often studied in isolation, giving an incomplete picture. A detailed, holistic characterisation of this group of people does not exist.
A robust characterisation of people with incurable cancer will allow identification and prioritisation of future research and has the potential to inform new therapeutics and provide justification for treatments.
This study aims to collect information about symptoms and quality of life, weight loss and body composition, physical activity and the body’s immune response to cancer.
Participants with incurable cancer will be recruited to the study from oncology and palliative medicine services in the UK. Participants will answer questionnaires about quality of life and symptoms, have bloods taken for inflammatory marker and cytokine analysis and have their body composition measured by a variety of methods.REC name
West of Scotland REC 3
REC reference
20/WS/0043
Date of REC Opinion
10 Mar 2020
REC opinion
Further Information Favourable Opinion