RETROSPECTIVE ANALYSIS OF RADIOTHERAPY TREATMENT OUTCOMES Version 1
Research type
Research Study
Full title
RETROSPECTIVE ANALYSIS OF THE EFFECTS OF DIFFERENT RADIOTHERAPY FRACTIONATION SCHEDULES AND OF DIFFERENCES IN BLOOD TEST RESULTS ON OUTCOMES IN CANCER PATIENTS
IRAS ID
125127
Contact name
Carolyn Taylor
Contact email
Research summary
This study by the University of Oxford will be a retrospective analysis of radiotherapy outcomes in cancer patients. The study will explore to what degree the efficacy of radiotherapy and the risk of side-effects depend on the dose of radiation received by the patient and the number of fractions in which the dose is delivered. In addition, it will examine whether the efficacy of radiotherapy is associated with various blood measurements before treatment begins. The data to be used in this study will be obtained from the National Cancer Registration Service and from participating hospitals. Data items will include radiotherapy dose and fractionation, other cancer treatments, cancer diagnosis and characteristics, comorbidities, patient characteristics, blood test results, cancer recurrence or second cancers, and death. A fully linked and anonymised datafile will be transferred to the University of Oxford for analysis.
The study is funded by Cancer Research UK and the University of Oxford. The first phase of the study is scheduled to last for three years and it is planned that a broader study will then be performed. Patients in the study will not be contacted. The study results will be of relevance to oncologists, to cancer patients, and to members of the general public, who may need treatment for cancer in the future.
REC name
South Central - Oxford A Research Ethics Committee
REC reference
13/SC/0610
Date of REC Opinion
19 Nov 2013
REC opinion
Favourable Opinion