Retinal non-perfusion in NPDR v PDR
Research type
Research Study
Full title
Retinal non-perfusion characteristics on ultra-widefield angiography in eyes with severe non-proliferative diabetic retinopathy and proliferative diabetic retinopathy
IRAS ID
244106
Contact name
Sobha Sivaprasad
Contact email
Sponsor organisation
University College London
Duration of Study in the UK
0 years, 1 months, 0 days
Research summary
We intend to perform a comparative study on the amount and distribution of reduced retinal perfusion in patients with severe non-proliferative diabetic retinopathy (no new blood vessels) and proliferative diabetic retinopathy (new blood vessel growth). Currently, the diagnosis is purely clinical and only eyes with proliferative diabetic retinopathy are treated. Therefore, identifying a threshold for the conversion to proliferative advanced diabetic retinopathy changes is required. This is a retrospective study reviewing images already taken of patients with severe non-proliferative diabetic retinopathy and proliferative diabetic retinopathy. These images are from previously completed studies and the images are all anonymized with no patient identifiable details used. The study will only involve image analysis performed in a single centre. The duration of the study is 4 weeks.
REC name
London - Westminster Research Ethics Committee
REC reference
18/LO/1640
Date of REC Opinion
21 Sep 2018
REC opinion
Favourable Opinion