Retention of people with psychosis in the EPOS trial V1
Research type
Research Study
Full title
Factors affecting retention of people with psychosis in the EPOS trial
IRAS ID
166717
Contact name
Paulina Szymczynska
Contact email
Sponsor organisation
Barts and the London School of Medicine and Dentistry
Duration of Study in the UK
0 years, 10 months, 28 days
Research summary
Recruitment and retention of participants is often the most challenging component of clinical trials. Poor recruitment and retention can be a major barrier to successful completion of studies. To date, there has been very little research looking into retention of people with psychosis in clinical trials. Studies investigating research attrition in other diagnostic groups often fail to consider the patients' perspective and are limited to the views of the researchers.
Understanding the participants' perspective on the factors affecting participation in trials is essential for ensuring ethical and effective conduct and successful completion of data collection.
This research will explore factors affecting retention of people with psychosis as research participants in trials evaluating non-pharmacological interventions. The objective is to understand how people with psychosis make decisions about remaining involved or dropping out of trials as research participants and what factors affect those decisions.
The knowledge about how people with psychosis make decisions about taking part in trials will help researchers and clinicians involved in the research process understand what support and information people need to make decisions that are right for them. It is also important that enough individuals take part in trials, so we hope to make some recommendations about what people with psychosis need and expect when participating in research.
This qualitative study will involve interviews with people with psychosis who have previously participated in a clinical trial and a) remained involved in the study and completed the intervention; b) remained involved in the study but did not complete the intervention; and c) joined the study but later dropped out completely.
We seek ethical approval to contact patients with psychosis (after prior consultation with their clinician) who have previously participated in a clinical trial evaluating a non-pharmacological intervention and invite them to take part in this qualitative study.REC name
London - Stanmore Research Ethics Committee
REC reference
15/LO/0991
Date of REC Opinion
30 Jun 2015
REC opinion
Further Information Favourable Opinion