RESPONSE TIME
Research type
Research Study
Full title
Assessing temporal response to Cardiac Resynchronisation Therapy
IRAS ID
332660
Contact name
BENJAMIN SIENIEWICZ
Contact email
Sponsor organisation
University Hospitals Plymouth NHS Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
The purpose of this study is to learn more about how people respond after they have a cardiac resynchronisation therapy (CRT) device implanted to treat your heart failure.
Heart failure is a condition where the heart is no longer able to function effectively as a pump. This causes the heart to become enlarged and can result in damage to the electrical conduction system of the heart, which tells the heart when and how to beat. During cardiac resynchronisation therapy (CRT), a pacing system is implanted below the left collar bone. This system includes a battery and some leads which are passed down to the heart and tell the heart when and how to beat. CRT is used in patients with damage to their conduction system to allow the heart to beat more effectively. This has been shown to improve symptoms of breathlessness, reduce the risk of being admitted to hospital with heart failure and ultimately reduce the risk of dying from heart failure.
It’s not clear how quickly CRT begins to have a beneficial effect. The CRT system begins to send electrical signals to the heart as soon as it is turned on, and while some patients report feeling better immediately, others do not experience any benefit up to a year after the procedure.
We want to look at how patients respond to CRT. Specifically, this project is designed to explore how quickly patients receive benefit from CRT and whether changes in some parameters occur sooner than others.REC name
London - Fulham Research Ethics Committee
REC reference
23/PR/1107
Date of REC Opinion
18 Dec 2023
REC opinion
Further Information Favourable Opinion