Respiratory Tissue Bank 2024

• Research type

  Research Tissue Bank

• IRAS ID

  339262

• Research summary

  Respiratory Tissue Bank

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  24/YH/0095

• Date of REC Opinion

  28 Jun 2024

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  This is a basic science study, which involves collecting samples from patients with respiratory viral infections, respiratory diseases, illnesses and relevant control subjects. Participants will be characterised on the basis of their lung function, the results of a physical examination and medical history, in accordance with internationally accepted criteria or the scientific requirements of the study. Healthy control participants will be recruited to enable comparative studies to be carried out. Written informed consent will be taken from participants prior to any data being collected or samples taken.

  Samples of blood, sputum, bronchial cells, biopsies, tracheal aspirates, nasal washes , breath samples and swabs may be collected to help with respiratory research. Cells and biopsies may be cultured in the laboratories to enable comparison of responses to disease relevant stimuli outside the body. The samples collected will be stored under an Human Tissue Authority (HTA) license.

• Research programme

  Synairgen aims to build a resource of samples that can be used to support respiratory research within the commercial and non-commercial sector. The data generated from the samples is intended to improve the prevention, diagnosis and treatment of respiratory diseases and illnesses, in particular viral induced episodes in asthmatic and COPD patients. Synairgen Research Ltd does not intend to sell samples to third parties. The intended purpose of sharing samples will be to support company initiatives and to explore new avenues for potential respiratory drug treatments and diagnostic developments. Samples will be shared with commercial and non-commercial entities working collaboratively with Synairgen Research Ltd within the respiratory field. Samples will also be shared with academic institutes to support academic research.

• Storage license

  12532

• RTBTitle

  Respiratory Tissue Bank

• Establishment organisation

  Synairgen Research Ltd

• Establishment organisation address

  Mailpoint 810, South Academic Block

  Southampton General Hospital

  Tremona Road, Southampton, Hampshire

  SO16 6YD