Respiratory health and wellbeing Post Pulmonary Tuberculosis (RESPOST)
Research type
Research Study
Full title
Respiratory health and wellbeing Post Pulmonary Tuberculosis (RESPOST): A Liverpool cross-sectional study pilot
IRAS ID
340073
Contact name
Rebecca Nightingale
Contact email
Sponsor organisation
Liverpool School of Tropical Medicine
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 5 months, 31 days
Research summary
We know that in low-income countries where there is a lot of tuberculosis (TB) about 50% of people treated for TB have long term problems with their lungs and general wellbeing. We don't if this is the case in UK (despite there being over new 5000 TB cases a year in the UK.
We would like to see if people who are treated in the Liverpool TB service have long term problems with their lungs. We will do this by inviting people who were treated for TB to come for a review at 1year after finishing treatment.
We will ask them to blow into a lung function testing machine (the same that is used for diagnosing asthma) and ask them questions about their health and wellbeing. If they have cough, we will ask them for a sputum sample and we will collect a blood sample if people are willing to donate a small amount of blood to be used in future research. We will also invite some people to partake in recorded interviews where they can give their opinion about how they feel having been treated for TB and what (if any) follow up they feel they would benefit from.
We hope that by recording the problems (if any) the people treated for TB have, we will then be able to use this data to design a larger UK-wide study investigating the prevalence of lung disease after treatment for TB. If we find that there is significant disease, in future we can then test treatment options and care pathways, as well as advocate for people to have improved follow up rather than just living with chronic lung health issues that might impair how well they can live their lives.REC name
London - Bloomsbury Research Ethics Committee
REC reference
25/LO/0204
Date of REC Opinion
7 Apr 2025
REC opinion
Further Information Favourable Opinion