Research using the National Chronic Kidney Disease Audit data
Research type
Research Database
IRAS ID
219521
Contact name
Dorothea Nitsch
Contact email
Research summary
National Chronic Kidney Disease Audit
REC name
London - Chelsea Research Ethics Committee
REC reference
17/LO/0049
Date of REC Opinion
3 Mar 2017
REC opinion
Further Information Favourable Opinion
Data collection arrangements
The National Chronic Kidney Disease Audit (NCKDA) collected between 2014-2016 data from 1057 general practices in England and Wales on testing of patients at risk of chronic kidney disease, as well as the identification and management of patients with chronic kidney disease. The current application is to allow the data to be used in future research of long term outcomes of Audit participants after the Audit ends, as otherwise the data would need to be deleted.
Anonymised clinical data will be stored at the London School of Hygiene & Tropical Medicine. Identifiable data (e.g. NHS numbers) will be stored separately in the secure data haven at the University College London.
Future data on the outcomes (e.g. hospitalisations, deaths, heart disease, acute kidney problems in the context of other illness, complete kidney failure with need of dialyis) of patients who provided data for the audit will be collected by linking the NHS numbers to clinical records held in other databases in the coming years, thus forming a large cohort study on outcomes and health needs of patients at risk of or with chronic kidney disease in primary care.
Research programme
If this application was approved, data from the National Chronic Kidney Disease Audit with its follow-up of health outcomes would provide a very large cohort study of kidney disease. The availability of additional information on those with advanced kidney disease held in the UK Renal Association Renal Registry would enable research across the entire patient journey from primary to secondary and then tertiary care. Many patients with kidney disease develop cardiovascular problems, and the present application would enable linkage to hospital records as well as to data on heart failure and heart attacks which are held at the National Institute for Cardiovascular Outcomes Research. Thus the proposed database would benefit both the renal and cardiovascular research community and provide important information that would help improve the clinical services for patients at risk of or with kidney disease.
Research database title
National Chronic Kidney Disease Audit
Establishment organisation
UCL Information Services Division
Establishment organisation address
University College London
Gower Street
WC1E 6BT