REPORT-BPD Feasibility Study
Research type
Research Study
Full title
Exploring Right vEntricular function applicability in a Prediction mOdel to identify pReterm infanTs with early BronchoPulmonary Dysplasia (REPORT – BPD Study): a mixed methods observational cohort feasibility study.
IRAS ID
311906
Contact name
WISAM MUHSEN
Contact email
Sponsor organisation
University Hospital Plymouth NHS Trust
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
What Bronchopulmonary dysplasia (BPD) stands for? \nBroncho - it affects the child’s air-passages; Pulmonary - it affects the child’s Lungs; Dysplasia - the child’s air-passages and lungs are not fully developed. \n\nWhat is the problem? \nBabies born early often need breathing support, which can hurt their fragile lungs. These injuries can lead to damage and scars in the lungs, which is called BPD. Every year BPD affects around seven thousand babies born before 32 weeks-of-gestation in the UK. Babies born so early, are expected to stay in the hospital between two to four months. This depends on how sick they are. \nIt is common that BPD causes poor body, brain growth and long-term breathing problems, which can lead to serious consequences, such as, disability or death. To date, we know very little about the early effect of BPD on the heart, the lungs small blood vessels and how they affect each other. Finding new ways to recognise early BPD will help clinicians provide treatment and studying future treatments to halt the progress of the disease. \n\nWhat are we trying to do? \nWe want to identify preterm infants with early BPD, through finding out how hard the heart is working in the affected babies. \n\nWhat will we do? \nFirst, we will search the recent studies to find an answer for our question; “What are the recent heart scan technologies used to find out how hard the heart’s right large chamber is working in babies born early?” This will be followed by a small study looking at how hard the right large chamber of the heart is working when early BPD is present in a preterm infant. This first study will help us in knowing if and how a larger study can be done.\n
REC name
South West - Central Bristol Research Ethics Committee
REC reference
22/SW/0023
Date of REC Opinion
16 Mar 2022
REC opinion
Further Information Favourable Opinion