Repeatability and reproducibility of ArcScan Insight 100
Research type
Research Study
Full title
Repeatability and reproducibility of corneal and anterior segment measurements by ArcScan Insight 100 very high-frequency digital ultrasound and comparison to optical coherence tomography
IRAS ID
186821
Contact name
Dan Reinstein
Contact email
Sponsor organisation
ArcScan Inc
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Very high-frequency (VHF) digital ultrasound is a technique that can measure individual layers within the cornea (the clear window at the front of the eye) with very high precision, as well as being able to image the interior of the eye including the chamber between the iris and the cornea, the lens and other structures behind the iris. VHF digital ultrasound has been used for imaging the eye for over 30 years and brings some advantages compared to other techniques.
Aside from the very precise corneal thickness measurement, VHF digital ultrasound enables measurement of the corneal epithelium (the layer of skin on the surface of the cornea), which can be used as a sensitive method of detecting a corneal disease known as keratoconus, as well as to diagnose the cause of poor vision due to an irregular cornea. VHF digital ultrasound can also be used for example to measure the thickness of a LASIK flap (laser eye surgery), or to measure the thickness of a corneal scar.
VHF digital ultrasound can also be used in the management of glaucoma and for lens implant surgery, particularly since the structures behind the iris can be imaged, whereas these are not visible for eye scanners based on light as the iris is not transparent. This allows the dimensions of the natural lens and the chamber behind the iris to be measured, which is crucial for deciding the optimal size for an artificial lens implant and for cataract surgery.
VHF digital ultrasound was commercialized in 1999 with the Artemis arc-scanner. In 2015, an upgraded version of this scanner has been developed, known as the ArcScan Insight 100. This study will aim to evaluate the precision of the new scanner and also to compare the measurements to a similar light-based scanner (optical coherence tomography).
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
15/WM/0319
Date of REC Opinion
22 Feb 2016
REC opinion
Further Information Favourable Opinion