REMARK

• Research type

  Research Study

• Full title

  A Retrospective Translational Study: Characterisation of Molecular Markers in Patients with Non-Hodgkin lymphoma.

• IRAS ID

  177762

• Contact name

  David Cunningham

• Contact email

  david.cunningham@rmh.nhs.uk

• Sponsor organisation

  The Royal Marsden NHS Foundation Trust

• Duration of Study in the UK

  2 years, 0 months, 0 days

• Research summary

  This is a retrospective study which aims at analysing biomarkers on archived samples from patients with Non-Hodgkin lymphoma (NHL) who have been treated at the Royal Marsden Hospital (RMH) between March 1990 and December 2014 and have surplus diagnostic tissue available for research.
  This study will evaluate the incidence and the predictive/prognostic value of several biomarkers in NHL. Assessment of DNA methylation and mutations are currently the main focus of this study, but other biomarkers including (but not limited to) DNA copy number changes, gene expression profiling and metabolites may be considered for analysis.

• REC name

  South Central - Berkshire B Research Ethics Committee

• REC reference

  16/SC/0132

• Date of REC Opinion

  24 Feb 2016

• REC opinion

  Favourable Opinion