Rejection, Immune Response and Timing of Kidney and Pancreas Transplan
Research type
Research Study
Full title
Rejection, Immune Response and Timing of Kidney and Pancreas Transplantation
IRAS ID
171145
Contact name
Stavros Papachristos
Contact email
Sponsor organisation
CMFT
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
There is evidence that, the immune system, the defence system of our body, follows a circadian rhythm in intensity and the way it responds to external assaults. Organ transplantation is indeed for the body an external attack, as a foreign organ is positioned in the body. With our project we aim to investigate the correlation of timing of transplantation with the immune response in order to achieve coordination of the immune system with the transplant organ. Thus, we will be able to maximise the outcome of transplantation, improve the graft and patient survival, minimise the rejection episodes and potentially reduce the needs for immunosuppression medication
REC name
North West - Greater Manchester Central Research Ethics Committee
REC reference
15/NW/0338
Date of REC Opinion
24 Jun 2015
REC opinion
Further Information Favourable Opinion