Rehabilitation for Individuals with Chronic Limb Threatening Ischemia
Research type
Research Study
Full title
Rehabilitation For Individuals With Chronic Limb Threatening Ischemia Post Revascularisation: A Co-created Feasibility Trial (HOPE)
IRAS ID
335894
Contact name
Stefan Birkett
Contact email
Sponsor organisation
Manchester University NHS Foundation Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
The prevalence of CLTI is growing and along with its associated health and social care burden. No studies have examined the effect of a rehabilitation programme on patients who undergo revascularisation for CLTI; therefore, these individuals are currently not offered a comprehensive rehabilitation programme as part of their treatment. This is a major missed opportunity in terms of improving CLTI care and outcomes, as access to rehabilitation has been shown to improve physical and social aspects of QoL in those with intermittent claudication, the lesser form of the disease.
This study aligns with the latest guidance and research priorities outlined by the American Heart Association, European Society of Cardiology and James Lind Alliance, the NHS’s long-term plan to improve outcomes for those with cardiovascular diseases, and the National Institute for Health and Care Research (NIHR) strategic focus of improving lives of people with long-term conditions.The study aims to test the feasibility of a rehabilitation intervention, that has been co-created for individuals with CLTI post-revascularisation surgery. The study will involve participants taking part in a 12-week exercise and education programme. The data collected from the study will include measures of recruitment and adherence, alongside assessments of physical function and quality of life.
REC name
London - Central Research Ethics Committee
REC reference
26/PR/0002
Date of REC Opinion
22 Jan 2026
REC opinion
Favourable Opinion