Reconstructive burden of wider excision margins

• Research type

  Research Study

• Full title

  Reconstructive burden and financial implications of wider excision margins for invasive primary cutaneous melanoma

• IRAS ID

  244766

• Contact name

  Marc Moncrieff

• Contact email

  marc.moncrieff@nnuh.nhs.uk

• Sponsor organisation

  Norfolk & Norwich University Hospital Foundation NHS Trust

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  For invasive primary cutaneous melanoma, a secondary wider excision around the original biopsy scar is advocated to reduce risk of local recurrence and improve patient outcomes. Surprisingly, the detail of the wide excision is still controversial and the management of patients with intermediate and high-risk primaries (AJCC pT2-pT4) is particularly ambiguous. International guidance on surgical margins for these groups of patients varies from 1 cm to 3cm (translating into large defects from 2 cm to 6 cm in maximum diameter) depending on Breslow thickness. The aim of this study isto determine the reconstructive and resource burden of wider excision margins.

• REC name

  London - Riverside Research Ethics Committee

• REC reference

  18/LO/0531

• Date of REC Opinion

  22 Mar 2018

• REC opinion

  Favourable Opinion