READ-OUT Observational Study
Research type
Research Study
Full title
READ-OUT – REAl world Dementia OUTcomes: Observational Study
IRAS ID
342412
Contact name
Vanessa Raymont
Contact email
Sponsor organisation
University of Oxford / Research Governance, Ethics and Assurance
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
A dementia diagnosis is usually made from speaking with patients and families, memory testing, and brain scans. While these methods are effective in identifying whether someone has dementia, they are not reliable when it comes to the cause of the condition or how it may progress in future.
Blood tests are a promising way to improve the diagnosis of dementia. But the research so far had participants who do not reflect real-world patient populations (for example in terms of their ethnicity or having other common illnesses).
Here, we aim to assess the usefulness of blood-based tests for dementia. The READ-OUT Observational Study investigates blood tests in people seen in memory clinics across the United Kingdom, for a wide variety of dementias and other memory problems. It will focus a lot of its recruitment from people from backgrounds that are not often involved in research: very elderly, ethnic minorities, those in deprived areas or with multiple illnesses, etc. We will also assess whether these tests are good value for money for the NHS. The project will show if blood biomarkers are useful for people attending NHS memory clinics.
REC name
Wales REC 7
REC reference
24/WA/0330
Date of REC Opinion
28 Oct 2024
REC opinion
Favourable Opinion