RCT of Cervical Dentine Sensitivty
Research type
Research Study
Full title
A Randomised Controlled Trial investigating a Comparison of Fluoride Varnish vs Self-Etching Dentine Bonding Agent in the Reduction of Cervical Dentine Sensitivity in Patients Attending a General Dental Practice in West Sussex, UK.
IRAS ID
204378
Contact name
Vatsal Amin
Contact email
Sponsor organisation
University of Kent
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
0 years, 2 months, 28 days
Research summary
Aim: to compare two well established treatment options in the management of dentine sensitivity.\n\nStudy title: “A Randomised Controlled Trial investigating a Comparison of Fluoride Varnish vs Self-Etching Dentine Bonding Agent in the Reduction of Cervical Dentine Sensitivity in Patients Attending a General Dental Practice in West Sussex, UK“.\n\nWhy? Cervical Dentine Sensitivity (CDS) is a common condition amongst dental patients estimated at affecting 15% of the population. It is characterised by a short, sharp pain and can be triggered by touch, cold or breathing cold air. There are several established treatment options for this condition but no gold standard. The purpose of the study is to further the dental community’s quest for a gold standard. This should help in treating patients with this potentially debilitating condition. \n\nWho and Where? Participants will be recruited from patients with CDS and already registered at the primary investigator’s general dental practice in West Sussex.\n\nHow? Following a robust consent process, willing participants with be asked to score sensitivity/pain levels on a Visual Analogue Scale following 2 different stimuli:\n1. Running cool water over the area\n2. Gentle air drying\nThe use of these stimuli is common practice in dentistry to diagnose CDS.\n\nWhat? The researcher will then apply one of two randomly assigned treatments to the affected area. Both interventions are simple non - invasive procedures involving painting on the gel/liquid with a soft brush. One is a fluoride gel (Duraphat Varnish by Colgate) and the second is a self-etching dentine bonding agent (Scotchbond Universal by 3M).\n\nAt the second appointment the pain the patient records scores again. This would conclude the data capture component of the study.\n\nFunding: the study is entirely self funded\n
REC name
North of Scotland Research Ethics Committee 1
REC reference
16/NS/0115
Date of REC Opinion
4 Nov 2016
REC opinion
Further Information Favourable Opinion