RAPID-CTCA
Research type
Research Study
Full title
Rapid Assessment of Potential Ischaemic Heart Disease with CTCA The role of early CT Coronary Angiography in the evaluation, intervention and outcome of patients presenting to the Emergency Department or Medical Assessment Unit with suspected or confirmed Acute Coronary Syndrome (The RAPID-CTCA Trial).
IRAS ID
164274
Contact name
Alasdair Gray
Contact email
Sponsor organisation
University of Edinburgh
ISRCTN Number
ISRCTN19102565
Clinicaltrials.gov Identifier
Duration of Study in the UK
3 years, 11 months, 31 days
Research summary
Rapid Assessment of Potential Ischaemic Heart Disease with CTCA (RAPID-CTCA)
Background and study aims
Recent advances in imaging technology have given us a non-invasive technique called computed tomography coronary angiography (CTCA). However, this technology has not been tested with patients presenting with suspected or confirmed acute coronary syndrome (ACS) (e.g. heart attack) to the Emergency Department (ED) in the UK. CTCA is capable of giving a better treatment of such patients with suspected or confirmed ACS. This study aims to find out the effect of early CTCA for Emergency Department patients with suspected or confirmed ACS, compared to current standard practice. We also would like to see if this would be cost-effective to use.Who can participate?
All patients aged 18 or over with suspected or confirmed ACS.What does the study involve?
Eligible participants will be approached in the ED or Medical Assessment Unit (MAU) and asked if they are willing to take part. They will be randomly allocated to CTCA in addition to standard care or standard care alone. During their admission and after 1, 6 and 12 months all participants will be asked to complete questionnaires about their symptoms, quality of life, satisfaction with their care and how often they have had to use healthcare services.Where is the study run from?
This study is being co-ordinated by the University of Edinburgh in collaboration with NHS Lothian. It will be run with local research teams in various hospitals throughout the UK.When is the study starting and how long is it expected to run for?
The study will start in January 2015 and will run until December 2018. Recruitment will take place between January 2015 and June 2017.Who is funding the study?
The study is funded by the National Institute for Health Research (NIHR)(UK).REC name
South East Scotland REC 01
REC reference
14/SS/1096
Date of REC Opinion
15 Dec 2014
REC opinion
Further Information Favourable Opinion