Quality of Life Post-ACS in Participants from EMMACE (EMMACE-XL) v1.0

• Research type

  Research Study

• Full title

  Health-related quality of life and clinical outcomes following acute myocardial infarction: The Evaluation of the Methods and Management of Acute coronary Events (EMMACE)-XL

• IRAS ID

  276202

• Contact name

  Chris Gale

• Contact email

  c.p.gale@leeds.ac.uk

• Sponsor organisation

  University of Leeds

• Clinicaltrials.gov Identifier

  https://bmjopen.bmj.com/content/5/6/e006256, published EMMACE protocol ; NCT01808027, EMMACE-3 ; NCT01819103, EMMACE-4

• Duration of Study in the UK

  3 years, 0 months, 1 days

• Research summary

  EMMACE-XL will recruit participants who are survivors of acute coronary syndrome (a type of heart attack) to assess their health-related quality of life five years or more after their heart attack. We will invite surviving participants from the EMMACE 3 and 4 studies to consent to participate in EMMACE-XL study, they will be asked to complete one questionnaire relating to their health, medication and lifestyle. The questionnaire will be linked to their data collected as part of the EMMACE 3 and 4 studies including long term follow up data from NHS Digital.
  The data collected from all the studies will then be analysed to see if patient groups can be identified who are at risk of poorer quality of life and worse health outcomes. These groups can then be targeted with the aim of improving their health outcomes.
  The study will use statistical methods to look at the relationship of factors such as; medication adherence, co-morbidities and patient demographics on health-related quality of life and health outcomes.
  The results of the study will be published in peer reviewed journals.
  Separate to this application, the British Heart Foundation has funded for a download of follow up data from NHS Digital, as per the original participant consent, to be applied for and processed. The HRQoL information, medication and lifestyle data collected as part of the EMMACE XL study will complement this additional NHS Digital download.
  All participants of EMMACE will be sent a privacy notice explaining how their data is processed by the University of Leeds.
  

• REC name

  London - London Bridge Research Ethics Committee

• REC reference

  20/PR/0104

• Date of REC Opinion

  31 Jul 2020

• REC opinion

  Further Information Favourable Opinion