Quality of life after open extremity trauma (QUINTET)
Research type
Research Study
Full title
Quality of life after open extremity trauma (QUINTET): a prospective, multi-centre, international study.
IRAS ID
295778
Contact name
Abhilash Jain
Contact email
Sponsor organisation
University of Oxford / Clinical Trials and Research Governance
Duration of Study in the UK
1 years, 6 months, 1 days
Research summary
Open lower limb fractures are life changing events. The management of these patients is complex and best accomplished by multidisciplinary teams. It takes a long time for patients to rehabilitate and many have permanent loss of function. According to the World Health Organisation, trauma remains relatively neglected in developing countries. We have studied the inequalities of access to treatment from a global perspective by assembling an international collaborative network on lower limb reconstruction (INTELLECT), including hospitals in 17 countries ranging from high to low income. We now plan to take advantage of this network to prospectively study the impact of open lower extremity fracture on the quality of life as these data have not been previously described in patients from medium and low-income countries. An international, prospective study will be set up and patients with open lower limb fractures willing to participate will be asked to complete two validated quality of life questionnaires. This will be the first step to design interventions to help trauma patients across different countries with varying income and healthcare systems from a mental health perspective.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
21/EE/0197
Date of REC Opinion
19 Oct 2021
REC opinion
Further Information Favourable Opinion