Qualitative study exploring symptoms and impact of IgAN

  • Research type

    Research Study

  • Full title

    Understanding Patients’ Experiences Of Symptoms And Impacts Of Immunoglobulin A Nephropathy (IgAN): A Qualitative Concept Elicitation Study

  • IRAS ID

    316188

  • Contact name

    Sarah Clifford

  • Contact email

    sarah.clifford@sprout-hs.com

  • Sponsor organisation

    Takeda

  • Duration of Study in the UK

    0 years, 2 months, 31 days

  • Research summary

    Immunoglobulin A nephropathy (IgAN) is a chronic and progressive disease that affects the kidneys. Over time as the functioning of the kidneys gets worse, people with IgAN experience a wide range of symptoms that get in the way of life; however, their experiences of symptoms and the impact of IgAN on daily life remain unexplored, particularly at the earlier stages of the disease. Therefore, the proposed study aims to address this research gap through 18 one-to-one audio-recorded interviews over the telephone or via videoconference with adults living with IgAN from different backgrounds and at different stages of the disease (early to mild) to build a better understanding of symptoms, their relative importance and impact on day-to-day life from the perspective of patients. The interview questions will be broad and open-ended so that the discussion is centred on what is important to each individual, e.g. Please tell me about the symptoms of your IgAN. It is expected that each interview will last 60 minutes. In the UK, participants will be recruited from one NHS secondary care service. The findings will reveal what matters most to people living with IgAN which in turn will ensure that the most meaningful and relevant outcomes related to symptoms and impact are measured to guide treatment decisions.

  • REC name

    South East Scotland REC 01

  • REC reference

    22/SS/0109

  • Date of REC Opinion

    6 Feb 2023

  • REC opinion

    Further Information Favourable Opinion