PUSH retrospective study on P-RMS and S-RMS

  • Research type

    Research Database

  • IRAS ID

    347826

  • Contact name

    Thuy-Giang Nguyen

  • Contact email

    Thuy-Giang.Nguyen@rmh.nhs.uk

  • Research summary

    International Multicentre Retrospective Study of P-RMS and S-RMS - PUSH Project

  • REC name

    East Midlands - Derby Research Ethics Committee

  • REC reference

    25/EM/0106

  • Date of REC Opinion

    14 May 2025

  • REC opinion

    Favourable Opinion

  • Data collection arrangements

    This database aims to retrospectively collect comprehensive data on patients of all ages diagnosed with pleomorphic rhabdomyosarcoma (P-RMS) and spindle cell/sclerosing rhabdomyosarcoma (S-RMS). The data collection will encompass a wide range of variables, including baseline demographics, clinical and histopathological characteristics, detailed records of locoregional and systemic treatments, specific regimen drugs used, best radiological response to treatment, and patient outcomes.

    Eligible patients will be identified at each participating centre following their standard practice. Each centre will have a unique patient ID and will assign a sequential patient ID to each case to maintain consistent tracking. Local site investigators will be responsible for entering the data into an electronic Case Report Form (eCRF) hosted on REDCap, a secure, web-based software platform designed for research data management.

  • Research database title

    International Multicentre Retrospective Study of P-RMS and S-RMS - PUSH Project

  • Establishment organisation

    Fondazione IRCCS Istituto Nazionale dei Tumori

  • Establishment organisation address

    via Giacomo Venezian 1

    Milano

    20133