PUGS (Paediatric Use of the AbbottSensorBasedGlucoseMonitoringSystem)

  • Research type

    Research Study

  • Full title

    Paediatric Use of the Abbott Sensor Based Glucose Monitoring System for 21 days – an Accuracy Evaluation

  • IRAS ID

    234355

  • Contact name

    Nicola Trevelyan

  • Contact email

    Nicola.Trevelyan@uhs.nhs.uk

  • Sponsor organisation

    Abbott Diabetes Care Ltd

  • Duration of Study in the UK

    0 years, 4 months, 31 days

  • Research summary

    The Abbott Sensor Based Glucose Monitoring System was CE marked in August 2014 for adults as the “FreeStyle Libre Flash Glucose Monitoring System”, with a wear duration of up to 14 days in adults. Post market clinical activities have included evaluation of the System and extension of the CE mark to its use in the paediatric population and for pregnant women. The aim of this investigation is to support a potential label extension for up to 21 days wear duration for children with diabetes.\nIt is the intention of this Clinical Investigation to evaluate the point accuracy and safety of the system in a paediatric population with wear duration of up to 21 days. The study is a multi-centre, single arm, prospective evaluation of the system. The target enrolment is approximately 110 subjects. Participants will be aged between 4 and 17 years. During the study, the Reader will be “masked“ - this means it will not show a glucose reading when scanning the Sensor. However, participants will be required to do at least four finger prick blood glucose (BG) tests per day and will be able to see these BG results on the Reader and to use this data for self management. The study is expected to last for approximately 4 months from first patient first visit to last patient last visit.\nEach participant will be in the study for a maximum of 35 days.

  • REC name

    Yorkshire & The Humber - Leeds West Research Ethics Committee

  • REC reference

    17/YH/0393

  • Date of REC Opinion

    13 Dec 2017

  • REC opinion

    Further Information Favourable Opinion