Psychophysical investigations of vision changes in glaucoma
Research type
Research Study
Full title
Psychophysical investigations of vision changes in glaucoma
IRAS ID
237660
Contact name
Jonathan Denniss
Contact email
Sponsor organisation
University of Bradford
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
This project aims to improve understanding of vision changes caused by glaucoma, potentially leading to improved vision tests useful for detection and monitoring of the disease.
Study participants will be people with glaucoma and age-similar healthy volunteers. Participants will visit the School of Optometry & Vision Science on 1-8 occasions, depending on which aspects of the study they take part in. Each visit will last a maximum of three hours.
Studies will involve eye and vision screening tests, identical to those performed during routine “high street” eye examinations, and new vision tests carried out on computer screens aiming to investigate specific aspects of vision. These tests will involve the participant viewing a computer screen from a fixed distance (maintained by placing their chin on a rest) and pressing buttons in response to patterns (e.g. spots, stripes, checkerboards) or images (e.g. everyday scenes) on the screen. Additionally, images of the eye will be captured using existing devices routinely used in “high street” optometry.
All procedures will be non-invasive, apart from the possible installation of eye drops to dilate the pupil and/or numb the front surface of the eye for eye pressure measurement. This is routinely carried out in “high street” optometry, and will only be carried out by suitably qualified optometrists. Taking part in any of the studies will not affect participants’ clinical care or disease in any way.
Data will be analysed to investigate differences in vision attributable to glaucoma, and how these differences relate to changes in the ocular structures.
We will also ask participants for permission to re-use the collected data in anonymised form in future studies. This may include wider dissemination of the data, e.g. through an open-access platform. Any such dissemination of data will be strictly anonymised with no possible identifying information included.
REC name
London - Brent Research Ethics Committee
REC reference
18/LO/0263
Date of REC Opinion
16 Feb 2018
REC opinion
Further Information Favourable Opinion