Prototype antibiotic susceptibility sensors for infected wounds V1.0
Research type
Research Study
Full title
Developing a device for the early detection of infection and antimicrobial susceptibility in diabetic foot ulcers
IRAS ID
195844
Contact name
Nishal Govindji-Bhatt
Contact email
Sponsor organisation
National Institute for Health Research (NIHR)
Duration of Study in the UK
0 years, 6 months, 0 days
Research summary
We have developed simple sensors that detect bacteria in patient’s wound exudate. The sensor permanently changes colour when exposed to pre-determined infectious levels of microorganisms. Additionally some of these sensors only change colour if organisms have resistance to particular antibiotics. By combining several of these sensors, information about the levels of microrganisms in the wound and their sensitivity to antimicrobial drugs will be clearly visible. Healthcare staff viewing this will immediately have information about the antibiotic drugs most likely to work.
In the current study we will confirm the performance of our sensors using ex-vivo worn wound dressing in vitro from a population of diabetic patients with foot ulcers.
REC name
East of Scotland Research Ethics Service REC 1
REC reference
16/ES/0066
Date of REC Opinion
27 Apr 2016
REC opinion
Favourable Opinion