Protocol Development of MRI with Healthy Volunteers
Research type
Research Study
Full title
Protocol Development of Magnetic Resonance Imaging with Healthy Volunteers
IRAS ID
258774
Contact name
Scott Semple
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
10 years, 0 months, 0 days
Research summary
Magnetic Resonance Imaging (MRI) is a non-invasive imaging technique using magnetic fields and radiowaves, with no ionising radiation involved. Scanning of healthy volunteers (not clinical patients) is an essential part of the development of clinical MRI research and clinical MRI service provision. Imaging protocols need to be tested and optimised in healthy volunteers before using them in patients, to make sure that the images produced are good enough to answer the research question being asked and to be valid for clinical interpretation/diagnosis. Edinburgh Imaging facilities currently have two MRI scanners and one PET-MRI scanner. This application covers MRI protocol development for all of these scanners, as well as any future MRI scanners operated by Edinburgh Imaging. Finalising the MRI protocol for PET-MRI is particularly important. The MRI duration is subsequently used to aid in calculation of the optimal radiation activity injected into study participants for the PET component of PET-MRI protocols, and therefore also the dose-risk assessment for PET-MRI studies. This application only covers imaging of healthy volunteers with MRI and therefore uses no ionising radiation. No PET protocol development is involved in this application.
REC name
South East Scotland REC 02
REC reference
20/SS/0123
Date of REC Opinion
10 Dec 2020
REC opinion
Further Information Favourable Opinion